Lumazine

Lumazine

$51.00 - 25 mg

$179.00 - 125 mg

All prices in Australian dollars

Code
BIA-L2672
Synonyms
2,4(3H,8H)-Pteridinedione, 2,4-Dihydroxypteridine, 2,4-Pteridinediol, NSC 225113, NSC 41801, Pteridine-2,4-dione
CAS #
487-21-8
Molecular Formula
C6H4N4O2
Molecular Weight
164.12
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Application Notes

Lumazine is a fluorescent pteridine occurring naturally in plants (Brassica juncea), insects (Formica polyctena) and the sea sponge Corallistes fulvodesmus, recently reviewed by Brimble and co-workers, University of Auckland, New Zealand. Lumazine is a photosensitizing agent, generating a singlet oxygen on UV irradiation. Lumazine is bactericidal to Methanobacterium thermoautotrophisum strain Marburg and is a selective inhibitor of methanogenesis used to improve the hydrogen production in microbial electrolysis cells.

References

  • Naturally occurring lumazines. Daniels B.J. et al. J Nat Prod. 2019, 82, 2054.
  • Tautomerism and fluorescence of lumazine. Klein R. et al. Photochem Photobiol. 1987, 45, 55.
  • The photosensitizing activity of lumazine using 2'-deoxyguanosine 5'-monophosphate and HeLa cells as targets. Denofrio P.M. Photochem Photobiol. Sci 2009, 8, 1539.

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