Ivermectin B1a aglycone
Ivermectin B1a aglycone
$280.00 - 1 mg
$980.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-I1151
- Synonyms
- Dihydroavermectin B1 aglycone, Ivermectin B1 aglycone
- CAS #
- 123997-59-1
- Molecular Formula
- C34H50O8
- Molecular Weight
- 586.8
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes
Ivermectin aglycone is a semi-synthetic produced by hydrolysing the disaccharide unit of ivermectin. Ivermectin aglycone is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance.
References
- Ivermectin, a new broad-spectrum antiparasitic agent. Chabala J.C. et al., J. Med. Chem. 1980, 23, 1134.
- Detection of resistance to ivermectin in Haemonchus contortus. Gill J.G. et al., Int. J. Parasit. 1991, 21, 771.