Hydroxycanthin-6-one, 4-

Hydroxycanthin-6-one, 4-

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-H1963
CAS #
106941-27-9
Molecular Formula
C14H8N2O2
Molecular Weight
236.23
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

Download Data Sheets

Product Data Sheet

Application Notes

4-Hydroxycanthin-6-one is a member of the canthin-6-one family isolated from Pentaceras australis Hook and its structure identified by Nelson and Price, CSIRO, Australia in 1952. Members of the family have been shown to bind to the benzodiazepine receptors of rat brain, to inhibit cAMP and to have anti-inflammatory activity and antimicrobial activity against Gram positive organisms and mycobacteria.

References

  • Alkaloids of the Australian Rutaceae: Pentaceras australis. III. Identification of 4-​Methylthiocanthin-​6-​one. Nelson E.R. & Price J.R. Aust J Sci Res, Ser B:  Biol Sci 1952, A5, 768.
  • Biomimetic approach to potential benzodiazepine receptor agonists and antagonists. Guzman F. et al. J Med Chem. 1984, 27, 564.
  • A new canthinone-​type alkaloid isolated from Ailanthus altissima swingle. Kim H.M. et al. Molecules 2016, 21, 642/1-642/10. 

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