Heronamide C is an unusual polyene macrocyclic lactam containing two isolated tetraene and triene chromophores. Heronamide C induces a unique reversible vacuolisation of mammalian tumor cells by an as yet unidentified mechanism.
- Heronamides A – C, new polyketide macrolactams from an Australian marine-derived Streptomyces sp. A biosynthetic case for synchronized tandem electrocyclization. Ritesh R. et al., Org. Biomol. Chem. 2010, 8, 4682.