Gramicidin complex

Gramicidin complex

$60.00 - 1 mg

$210.00 - 5 mg

All prices in Australian dollars

Code
BIA-G1592
CAS #
1405-97-6
Molecular Formula
C99H139N19O18 (for Gramicidin A1)
Molecular Weight
1883.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Gramicidins are a family of linear pentadecapeptides isolated from Bacillus brevis by Dubos at the Rockefeller Institute in 1939. Gramicidin is a complex of six closely related analogues A1, A2, B1, B2, C1 and C2 where A1 and A2 are the dominant components. Gramidicins act by forming channels in cell membranes causing ion leakage, and is an essential bioprobe for understanding the nature of the cell membranes.

References

  • Studies on a bactericidal agent extracted from a soil bacillus: I. Preparation of the agent. Its activity in vitro. Dubos R.J. J. Exp. Med, 1939, 70, 1.
  • The isolation of bacterial substances from cultures of Bacillus brevis. Hotchkiss R.D. & Dubos R.J. J. Biol. Chem. 1941, 141, 155.
  • Gramicidin A. I. Determination of composition and amino acid configuration by enzymatic and gas chromatographic methods. Ishii S-I. & Witkop B. J. Am. Chem. Soc. 1963, 85, 1832.

Other Products

Related products