Geodin

Geodin

Geodin

$265.00 - 1 mg

$930.00 - 5 mg

All prices in Australian dollars

Code
BIA-G3148
Synonyms
(+)-Geodin, d-Geodin, Estin
CAS #
427-63-4
Molecular Formula
C17H12Cl2O7
Molecular Weight
399.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Geodin is an unusual chlorine-containing metabolite produced by Aspergillus terreus first reported by Raistrick and Smith, University of London, England in 1936. Geodin is active against Newcastle disease virus with MIC 9 µg/mL in a chick embryo fibroblast system. Geodin has moderate activity against Gram-positive bacteria and possesses weak insecticidal activity. Geodin inhibits α-glucosidase and enhances fibrinolysis via plasminogen activator inhibition.

References

  • Studies in the biochemistry of micro-organisms: The metabolic products of Aspergillus terreus Thom. Part II. Two new chlorine-containing mould metabolic products, geodin and erdin. Raistrick H. & Smith G. Biochem. J. 1936, 30, 1315.
  • Studies on antiviral and antitumor antibiotics. XII. Effect of geodin on virus multiplication. Takatsuki A. et al. Agr. Biol. Chem. 1969, 33, 1119.
  • Design, semisynthesis, insecticidal and antibacterial activities of a series of marine-derived geodin derivatives and their preliminary structure-activity relationships. Chao R. et al. Mar. Drugs 2022, 18, 82.

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