Fusapyrone
Application Notes
Fusapyrone is a broad spectrum antifungal metabolite isolated from several Fusarium species, first reported in 1994. Fusapyrone exhibits low zoo-toxicity as evidenced by a lack of toxicity against Artemia salina, and is a useful candidate for control of postharvest crop diseases. The mechanism of action of fusapyrone is unknown. The structure of fusapyrone was revised in 2006.
References
- Fusapyrone and deoxyfusapyrone, two antifungal alpha-pyrones from Fusarium semitectum. Evidente A. et al., Nat. Toxins 1994, 2, 4.
- Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum. Altomare C. J. Agric. Food Chem. 2004, 52, 2997.
- Isolation and structure elucidation of neofusapyrone from a marine-derived Fusarium species, and structural revision of fusapyrone and deoxyfusapyrone. Hiramatsu F. et al., J. Antibiot. 2006, 59, 704.