Fumitremorgin C

Fumitremorgin C

$280.00 - 0.25 mg

$980.00 - 1 mg

All prices in Australian dollars

Molecular Formula
Molecular Weight
>95% by HPLC
Long Term Storage
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognised fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.


  • Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C. Allen J.D. et al., Mol. Cancer Ther. 2002, 1, 417.
  • Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Rabindran S.K. et al., Cancer Res. 2000, 60, 47.
  • Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. I. Taxonomy, fermentation, isolation and biological properties. Cui C.B. et al., J. Antibiot. 1996, 49, 527.

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