Erythromycin Degradation Set
Application Notes
Erythromycin A is a structurally complex macrocyclic lactone which can be degraded by acidity, alkalinity, heat, oxidation, light and temperature. In vivo, erythromycin A may also undergo enzymic conversions via hydrolysis, oxidation, derivatisation and coupling. The degradation products are not biologically inert; rather, they offer new structures with unique physical and chemical properties that are often poorly understood. The Erythromycin Degradation Set provides the major degradation products described in the literature as a tool for understanding the complexity of erythromycin degradation in both in vivo and ex vivo systems. | 1. Erythromycin A – (CAS# 114-07-8) – Molecular Formula: C37H67NO13 – Molecular Weight: 733.9 |
2. Anhydroerythromycin A – (CAS# 23893-13-2) – Molecular Formula: C37H65NO12 – Molecular Weight: 715.9 |
3. Erythromycin A enol ether – (CAS# 33396-29-1) – Molecular Formula: C37H65NO12 – Molecular Weight: 715.9 |
4. Erythromycin A N-oxide – (CAS# 992-65-4) – Molecular Formula: C37H67NO14 – Molecular Weight: 749.9 |
5. Pseudoerythromycin A enol ether – (CAS# 105882-69-7) – Molecular Formula: C37H65NO12 – Molecular Weight: 715.9