Erythromycin 2′-propionate
Application Notes
Erythromycin 2-propionate is the propionic acid ester precursor of erythromycin, the 14-membered macrocyclic lactone produced by Streptomyces erythreus. Erythromycin propionate displays an MIC of 0.01 – 0.05 ug/mL when tested against Micrococcus luteus.
References
- llotycin, a new antibiotic. McGuire J.M. et al. Antibiot Chemother 1952, 2, 281.2.
- Antibiotic glycosides. V. A comparison of 2-methylmalonate and propionate as precursors of the C21 branched-chain lactone in erythromycin. Friedman S.M. et al. J Biol Chem. 1964, 239, 2386.
- Derivatives of erythromycin, clarithromycin, roxithromycin or azithromycin with antibiotic and mucolytic activity Schickaneder H. et al. WIPO (PCT) WO2000023081A1.