Enterobactin, apo-

Enterobactin, apo-

$150.00 - 0.10 mg

$525.00 - 0.50 mg

All prices in Australian dollars

Code
BIA-E2282
CAS #
30414-16-5
Molecular Formula
C30H29N3O16
Molecular Weight
687.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Application Notes

apo-Enterobactin is the ring-opened form of enterobactin (enterochelin). apo-Enterobactin is a catecholate siderophore and a potent inhibitor of methylperoxidase (MPO) and lactoperoxidase (LPO) activity in the inflamed gut, reducing MPO activity in a dose-related manner.

References

  • Structures of enterochelin and related 2,3-dihydroxy-N-benzoylserine conjugates from Escherichia coli. O’Brien I.G. & Gibson F. Biochim Biophys Acta 1970, 215, 393.
  • Identification of enterobactin and linear dihydroxybenzoylserine compounds by HPLC and ion spray mass spectrometry (LC​/MS and MS​/MS). Berner I. et al. Biol Metals 1991, 4, 113.
  • Interplay between enterobactin, myeloperoxidase and lipocalin 2 regulates E. coli survival in the inflamed gut. Singh et al. Nature Comm. 2015, 6, 7113.

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