Enniatin B1

Enniatin B1

$225.00 - 1 mg

$790.00 - 5 mg

All prices in Australian dollars

Code
BIA-E1168
Synonyms
2-(N-Methyl-L-isoleucine)enniatin B
CAS #
19914-20-6
Molecular Formula
C34H59N3O9
Molecular Weight
653.9
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Product Data Sheet

Application Notes

Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin B1 is one of four major analogues of the enniatin complex.

References

  • Ionophore antibiotics produced by the fungus Fusarium orthoceras var. enniatum and other Fusaria. Gaumann E. et al., Experientia 1947, 3, 202.
  • "Sandwich" complexation in cyclopeptides and its implications in membrane processes. Ivanov V.T. Ann. N. Y. Acad. Sci. 1975, 264, 221.
  • Interaction of cyclic peptides and depsipeptides with calmodulin. Mereish K.A. et al., Pept. Res. 1990, 3, 233.
  • Enniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells. Dornetshuber R. et al., Chem. Res. Toxicol. 2007, 20, 465.

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