Emeguisin A

Emeguisin A

$158.00 - 0.10 mg

$553.00 - 0.50 mg

All prices in Australian dollars

CAS #
117032-54-9
Molecular Formula
C23H23ClO5
Molecular Weight
414.9
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
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Application Notes

Emeguisin A was first isolated from the fungus Emericella unguis by Yamakazaki and coworkers from Hoshi University, Japan in 1988. Emeguisin A exhibits potent antibacterial activity against Staphylococcus aureusincludin methicillin-​resistant strains, as well as strong antifungal activity against Cryptococcus neoformans, each with MIC values of 0.5 μg​/mL.

References

  • Studies on fungal products. Part 22. Isolation and structures of novel fungal depsidones, emeguisins A, B, and C, from Emericella unguis. Kawahara N. et al. J Chem Soc Perkin Trans I Org Bioorg Chem. 1988, 9, 2611.
  • Depsidone and phthalide derivatives from the soil-derived fungus Asperguillus unguis PSU-RSPG199. Tet Lett. 2016, 57, 4348.
  • Expanding the chemical space around the nidulin pharmacophore. Morshed M.T. et al. Org Biomolec Chem. 2018, 16, 3038.

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