Echinocandin B

Echinocandin B

$300.00 - 1 mg

$1,050.00 - 5 mg

All prices in Australian dollars

Code
BIA-E1253
Synonyms
A 30912, A 22082, 7810, SL 7810F
CAS #
54651-05-7
Molecular Formula
C52H81N7O16
Molecular Weight
1060.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

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Product Data Sheet

Application Notes

Echinocandin B is the major analogue of a family of lipopeptides isolated from several species of Aspergillus, reported in 1974. Echinocandin B is a potent antifungal and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.

References

  • Metabolites of microorganisms. 143. Echinocandin B, a novel polypeptide-antibiotic from Aspergillus nidulans var. echinulatus: isolation and structural components. Nyfeler R. & Keller-Schierlein W. Helv Chim Acta. 1974, 57, 2459.
  • Lysis of growing yeast-form cells of Candida albicans by echinocandin: a cytological study. Cassone A. et al., Sabouraudia 1981, 19, 97.
  • Echinocandin inhibition of 1,3-beta-D-glucan synthase from Candida albicans. Sawistowska-Schröder E. T. et al., FEBS Lett. 1984, 173, 134.

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