Dihydro-6-hydroxypenicillic acid

Dihydro-6-hydroxypenicillic acid

$240.00 - 0.50 mg

$840.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-H2961
Synonyms
5,6-Dihydro-6-hydroxypenicillic acid
CAS #
1661837-02-0
Molecular Formula
C8H12O5
Molecular Weight
188.18
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Dihydro-6-hydroxypenicillic acid is a butenolide/butyrolactone mycotoxin produced by various Penicillium, Aspergillus and other species. Dihydro-6-hydroxypenicillic acid has antiviral activity and has been patented as an antifouling agent for marine coatings. Dihydro-6-hydroxypenicillic acid inhibits influenza A/WSN/ 33 virus with an IC50 of 68 ± 0.7 µM. Dihydro-6-hydroxypenicillic acid is reported to be a nerve growth factor activator.

References

  • Butenolide compounds for antifouling agent use in marine coatings. Qi S. et al. China, CN104356730 A 2015-02-18.
  • New butyrolactone derivatives from the endophytic Fungus Talaromyces sp. CPCC 400783 of Reynoutria japonica Houtt. Zhang R. et al. J Antibiot. 2021, 74, 225.

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