Diacetylcercosporin
Application Notes
Diacetylcercosporin is a minor hydrophobic analogue of cercosporin produced by several species of the fungal genera, Cercospora and Septoria. Diacetylcercosporin has moderate in vitro activity against Leishmania and chloroquine-sensitive strains of Plasmodium falciparum. Diacetylcercosporin exhibits antitumor activity. Like other perylenequinones, the biological activity of diacetylcercosporin is significantly enhanced on light-activation.
References
- Cercosporin. A pigment of Cercosporina kikuchii Matsumoto et Tomoyasu. I. Cultivation of fungus, isolation and purification of pigment. Kuyama S. & Tamura T. J. Am. Chem. Soc. 1957, 79, 5725.
- Antiprotozoan and antimicrobial compounds from the plant pathogen Septoria pistaciarum. Kumarihamy M. et al., J. Nat. Prod. 2012, 75, 883.