Deoxynivalenol is a trichothecene mycotoxin produced by various Fusarium sp. infecting grains. Deoxynivalenol has immunosuppressant activity, inducing activator protein-1 (AP-1) activity in the murine EL-4 thymoma model which may contribute to cytokine dysregulation and immunotoxic effects associated with exposure to trichothecene mycotoxins. Deoxynivalenol is an emetic and has weak Gram positive antibiotic activity.
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