Deoxynivalenol

Deoxynivalenol

$180.00 - 0.10 mg

$630.00 - 0.50 mg

All prices in Australian dollars

Code
BIA-D1928
Synonyms
DON, NSC 269144, Vomitoxin
CAS #
51481-10-8
Molecular Formula
C15H20O6
Molecular Weight
296.32
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

Deoxynivalenol is a trichothecene mycotoxin produced by various Fusarium sp. infecting grains. Deoxynivalenol has immunosuppressant activity, inducing activator protein-​1 (AP-​1) activity in the murine EL-​4 thymoma model which may contribute to cytokine dysregulation and immunotoxic effects associated with exposure to trichothecene mycotoxins. Deoxynivalenol is an emetic and has weak Gram positive antibiotic activity.

References

  • Fusarium species pathogenic to barley and their associated mycotoxins. Salas B. et al. Plant Dis. 1999, 83, 667.
  • Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol). Li S. et al. Tox Appl Pharmacol. 2000, 163, 17.
  • Deoxynivalenol impairs the immune functions of neutrophils. Gauthier T. et al. Mol Nutr Food Res. 2013, 57, 1026.

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