Deoxygerfelin

Deoxygerfelin

$215.00 - 1 mg

$755.00 - 5 mg

All prices in Australian dollars

Code
BIA-D1850
Synonyms
4-Carboxydiorcinal
CAS #
36149-01-6
Molecular Formula
C15H14O5
Molecular Weight
274.27
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Deoxygerfelin was isolated from a mutagen-treated strain of Aspergillus fumigatus that failed to produce fumigatin and spinulosin, by researchers at Kanazawa University, Japan in 1972. Deoxygerfelin is closely related to gerfelin, a metabolite isolated from Beaveria felina as a geranylgeranyl diphosphatate synthase inhibitor. The biological profile of deoxygerfelin is largely unexplored.

References

  • Metabolic products of a strain of Aspergillus fumigatus DH 413. V. New metabolite produced by ethionine inhibition. Yamamoto Y. et al., Chem. Pharm. Bull. 1972, 20, 931.
  • Gerfelin, a novel inhibitor of geranylgeranyl diphosphate synthase from Beauveria felina QN22047. I. Taxonomy, fermentation, isolation, and biological activities. Zenitani S. et al., J. Antibiot. 2003, 56, 617.

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