$302.00 - 0.50 mg
$1,057.00 - 2.50 mg
All prices in Australian dollars
- AY 26623
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.
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O-Deacetylravidomycin is the more active and stable analogue of the ravidomycin complex produced by Streptomyces ravidus. The metabolite shows potent, light-dependent antitumor activity. O-Deacetylravidomycin, like the related gilvocarcins and chrysomycins, is thought to act as a topoisomerase II inhibitor.
- New ravidomycin analogues, FE35A and FE35B, apoptosis inducers produced by Streptomyces rochei. Yamashita N. et al., J. Antibiot. 1998, 51, 1105.
- Biochemical characterisation of elsamicin and other coumarin-related antitumor agents as potent inhibitors of human topoisomerase II. Lorico A. et al., Eur. J. Cancer 1993, 29A, 1985.
- Light-dependent activity of the antitumor antibiotics ravidomycin and desacetylravidomycin. Greenstein M. et al., Antimicrob. Agents Chemother. 1986, 29, 861.