Coumaric acid, p-

Coumaric acid, p-

$65.00 - 5 mg

$230.00 - 25 mg

All prices in Australian dollars

4-Coumaric acid; 4-Hydroxycinnamic acid; 4'-Hydroxycinnamic acid; NSC 59260; NSC 674321; p-Cumaric acid; p-Hydroxycinnamic acid; p-Hydroxyphenylacrylic acid; b-[4-Hydroxyphenyl]acrylic acid
Molecular Formula
Molecular Weight
>95% by HPLC
Long Term Storage
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

p-Coumaric acid is a common plant metabolite, biosynthetically formed by the action of tyrosine ammonia-lyase (TAL) on phenylalanine. p-Coumaric acid is a member of the phenylpropanoid class of lignin biosynthetic precursors. p-Coumaric acid is readily produced by fermentation on media containing plant extracts. The biochemical and pharmacological activity of p-coumaric acid has > 10,000 SciFinder entries and the area is well reviewed by Guzman (2014) and Sharma (2011). p-Coumaric acid a useful standard for analytical and bioassay dereplication.


  • Metabolomics-guided analysis of isocoumarin production by Streptomyces species MBT76 and biotransformation of flavonoids and phenylpropanoids. Wu C. et al., Metabolomics 2016, 12, 1.
  • Expanding the chemical space for natural products by Aspergillus-Streptomyces co-cultivation and biotransformation. Wu C. et al., Scientific Reports 2015, 5, 10868.
  • p-Hydroxycinnamic acid production directly from cellulose using endoglucanase- and tyrosine ammonia lyase-expressing Streptomyces lividans. Kawai Y. et al., Microbial Cell Factories 2013, 12, 45.
  • Cinnamic acid derivatives: A new chapter of various pharmacological activities. Sharma P., J. Chem. Pharm. Res. 2011, 3, 403.

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