Cladobotric acid H

Cladobotric acid H

$315.00 - 1 mg

$1,105.00 - 5 mg

All prices in Australian dollars

Code
BIA-C3201
Synonyms
-
CAS #
2900278-39-7
Molecular Formula
C27H36O5
Molecular Weight
440.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

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Application Notes

Cladobotric H is an unusual polyketide isolated from Cladobotryum sp. grown on rice in 2022. Cladobotric H displays moderately potent activity against S. aureus, including MSSA, MRSA/VISA and hVISA. Cladobotric acid H displays significant antifungal activity against Aspergillus fumigatus and Candida auris. Cladobotric acid H is more potent than cladobotric acid E as an antibacterial, but less potent as an antifungal.

References

  • Cladobotric acids: Metabolites from cultures of Cladobotryum sp., semisynthetic analogues and antibacterial activity. J. Nat. Prod. Doa T-T. et al. 2022, 85, 572.
  • Hakuhybotrol, a polyketide produced by Hypomyces pseudocorticiicola, characterized with the assistance of 3D ED/MicroED. Watanabe Y. et al. Org. Biomol. Chem. 2023, 21, 2320.

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