Chevalone E

Chevalone E

$230.00 - 0.50 mg

$805.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-C1879
Synonyms
Deacetylchevalone C
CAS #
1315451-94-5
Molecular Formula
C26H38O4
Molecular Weight
414.58
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Chevalone E is a minor analogue of the meroterpenoid chevalone family, isolated from Aspergillus similanensis by researchers in Portugal. Chevalone E is closely related to the aszonapyrones and sartorypyrones. Chevalone E is synergistic when used with oxacillin against methicillin-resistant Staphylococcus aureus (MRSA) but not with ampicillin. Other members of the chevalone family show weak activity against Mycobacterium tuberculosis and tumor cell lines.

References

  • New isocoumarin derivatives and meroterpenoids from the marine sponge-associated fungus Aspergillus similanensis sp. nov. KUFA 0013. Prompanya C. et al., Mar. Drugs 2014, 12, 5160.
  • Bioactive meroterpenoids and alkaloids from the fungus Eurotium chevalieri. Kanokmedhakul K. et al., Tetrahedron 2011, 67, 5461.
  • Chevalone C analogues and globoscinic acid derivatives from the fungus Neosartorya spinosa KKU-1NK1. Rajachan O. et al., Phytochem. 2016, 132, 68.

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