Chelidonic acid

Chelidonic acid

$56.00 - 25 mg

$196.00 - 100 mg

All prices in Australian dollars

Code
BIA-C2572
Synonyms
Jerva acid, Jervaic acid, Jervasic acid, NSC 3979
CAS #
99-32-1
Molecular Formula
C7H4O6
Molecular Weight
184.1
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

Download Data Sheets

Product Data Sheet

Application Notes

Chelidonic acid occurs in numerous plants, including Chelidonium majus. Chelidonic acid has anti-inflammatory and immunomodulatory activity, inhibiting mast cell degranulation and IL-6 prodution by blocking NF-​κB and caspase-​1 in HMC-​1 cells. Chelidonic acid up-regulates BNDF in animal models, evoking an antidepressant-like effect.

References

  • Occurrence and distribution of chelidonic acid in various plant families. Ramstad E. Pharm Acta Helvetiae 1953, 28, 4145.
  • Effects of chelidonic acid, a secondary plant metabolite, on mast cell degranulation and adaptive immunity in rats. Singh K. et al. Int Immunopharmacol. 2016, 40, 229.
  • Inhibitory effects of chelidonic acid on IL-​6 production by blocking NF-​κB and caspase-​1 in HMC-​1 cells. Shin H-Y. et al. Immunopharmacol Immunotox. 2011, 33, 614.

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