Butyrolactone II is one of a family of four butyrolactones isolated from the fungus, Aspergillus terreus, by Yamamoto and collaborators at Kanazawa University, Japan in 1983. Butyrolactone II inhibits soybean lipoxygenase (LOX) and α-glucosidase. Butyrolactone II has antioxidant activity via DPPH radical-scavenging.
- Metabolic products of Aspergillus terreus. IX. Biosynthesis of butyrolactone derivatives isolated from strains IFO 8835 and 4100. Nitta K. et al., Chem. Pharm. Bull. 1983, 31, 1528.
- Soybean lipoxygenase inhibitory and DPPH radical-scavenging activities of aspernolide A and butyrolactones I and II. Sugiyama Y. et al., Biosci. Biotechnol. Biochem. 2010, 74, 881.
- Effect on α-glucosidase inhibition and antioxidant activities of butyrolactone derivatives from Aspergillus terreus MC751. Dewi T.R. et al., Med. Chem. Res. 2014, 23, 454.