Burnettramic acid A

Burnettramic acid A

$158.00 - 0.25 mg

$553.00 - 1 mg

All prices in Australian dollars

CAS #
2334483-46-2
Molecular Formula
C41H71NO12
Molecular Weight
770
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

Burnettramic acid and its aglycone are members of a new class of antibiotics from an Australian fungus Aspergillus burnettii.  The rare bolaamphiphilic scaffold consists of β-​d-​mannose linked to a pyrrolizidinedione unit via a 26-​carbon chain. Burnettramic acid A is a potent antifungal.

References

  • Discovery and Heterologous Biosynthesis of the Burnettramic Acids: Rare PKS-​NRPS-​Derived Bolaamphiphilic Pyrrolizidinediones from an Australian Fungus, Aspergillus burnettii. Hang L. et al. Org lett 2019, 21, 1287.
  • Comprehensive chemotaxonomic and genomic profiling of a biosynthetically talented Australian fungus, Aspergillus burnettii sp. nov. Gilchrist C. et al. FG & B 2020, 143, 103435.  

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