Blasticidin S

Blasticidin S

$100.00 - 1 mg

$350.00 - 5 mg

All prices in Australian dollars

Code
BIA-B1425
Synonyms
Cytovarin, Bla-S, 21544, A83094C, NSC 91770
CAS #
2079-00-7
Molecular Formula
C17H26N8O5
Molecular Weight
422.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

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Application Notes

Blasticidin S is a nucleoside produced by several species of Streptomyces, first reported in the late 1950s. Blasticidin S is an antifungal agent with particularly potent activity against the rice pathogen, Piricularia oryzae, for which it was used commercially for some time in Japan. Blasticidin S inhibits protein synthesis and is active against bacteria, tumor cell lines and nematodes. More recently, blasticidin S has been used as a marker for strain manipulations. Blasticidin S provided by BioAustralis is presented as the free base to avoid problems associated with the use of the hydrochloride.

References

  • Blasticidin S, a new antibiotic. Takeuchi S. et al., J. Antibiot. 1958, 11, 1.
  • Nucleoside antibiotics. Suhadolnik R.J. pub. Wily-Interscience. 1970, 298.
  • Blasticidin S-resistance gene (bsr): a novel selectable marker for mammalian cells. Izumi M. et al., Exp. Cell Res. 1991, 197, 229.

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