Bilaid B1

Bilaid B1

$263.00 - 1 mg

$921.00 - 5 mg

All prices in Australian dollars

CAS #
NA
Molecular Formula
C28H39N5O5
Molecular Weight
525.7
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

The bilaids are tetrapeptides with an unusual alternating LDLD chirality isolated from an Australian estuarine isolate of Penicillium sp.. Bilaids are weak μ-opioid agonists (Ki = 3.1 µM using HEK293 cell membranes expressing the human receptor) that inhibit forskolin-induced cAMP accumulation in HEK293 cells expressing the human µ-opioid receptor by 21% when used at a concentration of 10 µM.

References

  • A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-​opioid receptor. Dekan Z et al. Proc Nat Acad Sci 2019, 116, 22535.

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