Bicyclomycin

Bicyclomycin

$305.00 - 1 mg

$1,070.00 - 5 mg

All prices in Australian dollars

Code
BIA-B1367
Synonyms
Bicozamycin, Aizumycin, Bacteron, CGP 3543E, WS4545, 5879
CAS #
38129-37-2
Molecular Formula
C12H18N2O7
Molecular Weight
302.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972. The selective Gram negative profile of bicyclomycin is rare among Streptomyces metabolites. The primary site of action for bicyclomycin is thought to be the rho transcription termination factor.

References

  • Bicyclomycin, a new antibiotic I. Taxonomy, isolation and characterization. Miyoshi T. et al., J. Antibiot. 1972, 25, 569.
  • Bicyclomycin, a new antibiotic II. Structural elucidation and acyl derivatives. Kamiya T. et al., J. Antibiot. 1972, 25, 576.
  • Transcription termination factor rho: The site of bicyclomycin inhibition in Escherichia. Zwiefka A. et al., Biochemistry 1993, 32, 3564.

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