Bestatin
Bestatin
$145.00 - 5 mg
$510.00 - 25 mg
All prices in Australian dollars
- Code
- BIA-B1278
- Synonyms
- Ubenamix, Inobestin, NK 421
- CAS #
- 58970-76-6
- Molecular Formula
- C16H24N2O4
- Molecular Weight
- 308.4
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Moderate water solubility.
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Application Notes
Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activating macrophages and T lymphocytes. Bestatin also exhibits antitumor activity and has been investigated in clinical trials.
References
- Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. Umezawa H. et al., J. Antibio. 1976, 29, 97.
- The structure of bestatin. Suda H. et al., J. Antibio. 1976, 29, 100.
- Low-molecular-weight enzyme inhibitors of microbial origin. Umezawa H. Ann. Rev. Microbiol. 1982, 36, 75.