Bestatin

Bestatin

$145.00 - 5 mg

$510.00 - 25 mg

All prices in Australian dollars

Code
BIA-B1278
Synonyms
Ubenamix, Inobestin, NK 421
CAS #
58970-76-6
Molecular Formula
C16H24N2O4
Molecular Weight
308.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Moderate water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activating macrophages and T lymphocytes. Bestatin also exhibits antitumor activity and has been investigated in clinical trials.

References

  • Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. Umezawa H. et al., J. Antibio. 1976, 29, 97.
  • The structure of bestatin. Suda H. et al., J. Antibio. 1976, 29, 100.
  • Low-molecular-weight enzyme inhibitors of microbial origin. Umezawa H. Ann. Rev. Microbiol. 1982, 36, 75.

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