Bafilomycin D

Bafilomycin D

$325.00 - 1 mg

$1,140.00 - 5 mg

All prices in Australian dollars

Code
BIA-B1162
Synonyms
Tubaymycin, 3D5
CAS #
98813-13-9
Molecular Formula
C35H56O8
Molecular Weight
604.8
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Bafilomycin D is a member of a potent family of macrocyclic lactones. Bafilomycin D shares the same mode of action as bafilomycin A1 which has been the analogue of choice in cell biology studies of the role of ATPase. Bafilomycin D contains the ring-opened side chain and is a much more stable analogue of bafilomycin A1. Limited availability has restricted a more in depth investigation of this metabolite.

References

  • The structure of novel insecticidal macrolides: bafilomycin D and E, and oxhygrolidin. Kretschmer A. et al., Agric. Biol. Chem. 1985, 49, 2509
  • Bafilolides, Potent Inhibitors of the Motility and Development of the Free-Living Stages of Parasitic Nematodes. Lacey E. et al., Int. J. Parasitol. 1995, 25, 349.

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