$270.00 - 1 mg
$945.00 - 5 mg
All prices in Australian dollars
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility. NOTE: forms methyl ketal on long term storage in methanol.
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Bafilomycin A1 is a member of a potent family of macrocyclic lactones with broad spectrum biological activity, including activity against bacteria, yeast, fungi, nematodes, insects and tumor cell lines. Bafilomycin A1 is an inhibitor of vacuolar-type ATPase.
- Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Bowman E.J. et al., Proc Natl Acad Sci USA. 1988, 85, 7972.
- Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. Yoshimori T. et al., J Biol Chem. 1991, 266, 17707.
- Vacuolar ATPase as a drug discovery target. Niikura K. Drug News Perspect. 2006, 19, 139.