Avilamycin A
Avilamycin A
$225.00 - 1 mg
$790.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-A2301
- CAS #
- 69787-79-7
- Molecular Formula
- C61H88Cl2O32
- Molecular Weight
- 1404.2
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in methanol or DMSO
Download Data Sheets
Application Notes
Avilamycin A is a chlorine-containing polysaccharide antibiotic produced by Streptomyces viridochromogenes. Avilamycin is active against Gram-positive bacteria and is used as a growth promotant and for prevention of necrotic enteritis in animals. Avilamycin binds to the 30S ribosome and resistance is conferred by rRNA methyl transferases. Avilamycin A is a major analogue in the commercial product Surmax™.
References
- Avilamycin. Buzzetti F. et al. Experientia 1968, 24, 320.
- Avilamycin, an inhibitor of the 30 S ribosomal subunits function. Wolf H. FEBS Lett 1973, 36, 181.
- An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tu57. Weitnauer G. et al. Antimicrob Agents Chemother 2001, 45, 690.
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