Avilamycin A

Avilamycin A

$221.00 - 1 mg

$774.00 - 5 mg

All prices in Australian dollars

Code
BIA-A2301
CAS #
69787-79-7
Molecular Formula
C61H88Cl2O32
Molecular Weight
1404.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

Avilamycin A is a chlorine-containing polysaccharide antibiotic produced by Streptomyces viridochromogenes. Avilamycin is active against Gram-positive bacteria and is used as a growth promotant and for prevention of necrotic enteritis in animals. Avilamycin binds to the 30S ribosome and resistance is conferred by rRNA methyl transferases. Avilamycin A is a major analogue in the commercial product Surmax™.

References

  • Avilamycin. Buzzetti F. et al. Experientia 1968, 24, 320.
  • Avilamycin, an inhibitor of the 30 S ribosomal subunits function. Wolf H. FEBS Lett 1973, 36, 181.
  • An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tu57. Weitnauer G. et al. Antimicrob Agents Chemother 2001, 45, 690.

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