Ariestatin A

Ariestatin A

Ariestatin A

$210.00 - 0.25 mg

$735.00 - 1 mg

All prices in Australian dollars

Code
BIA-A3211
Synonyms
-
CAS #
-
Molecular Formula
C34H48O12
Molecular Weight
648.8
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Ariestatin A is a major component of a parallel series of analogues of aquastatin A, a metabolite previously isolated from Fusarium aquaeductuum and re-isolated from the fungus Austroacremonium gemini. Ariestatin A is a lower homologue (C13 side-chain) of aquastatin A (C15 side-chain). Ariestatin A exhibits potent antibacterial activity against antibiotic-susceptible and resistant strains and no cytotoxic activity.

References

  • The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains. Sbaraini N. et al. Chem. Sci. 2024, 15,18872.
  • Aquastatin A, an inhibitor of mammalian adenosine triphosphatases from Fusarium aquaeductuum. Taxonomy, fermentation, isolation, structure determination and biological properties. Hamano K. et al. J Antibiot 1993, 46, 1648.

Other Products

Related products