Apicidin

Apicidin

$165.00 - 2 mg

$578.00 - 10 mg

All prices in Australian dollars

Code
BIA-A1006
CAS #
183506-66-3
Molecular Formula
C34H49N5O6
Molecular Weight
623.8
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Clear

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Application Notes

Apicidin is a cyclic peptide antibiotic with broad spectrum antiparasitic and antiprotozoan activity. Apicidin, a histone deacetylase inhibitor, is anti-angiogenic and induces apoptosis.

References

  • Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Han J.W. et al., Cancer Res. 2000, 60, 6068.
  • Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials. Kim S.H. et al., Biochem. Biophys. Res. Commun. 2004, 315, 964.

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