Apicidin D2

Apicidin D2

$235.00 - 1 mg

$825.00 - 5 mg

All prices in Australian dollars

Code
BIA-A2984
CAS #
177562-78-6
Molecular Formula
C34H51N5O6
Molecular Weight
625.8
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Apicidin D2 is the 8’S-alcohol derivative of apicidin, produced by Fusarium sp.. While there is minimal published data on the biological activity of apicidin D2, the apicidins are histone deacetylase inhibitors and have potent and broad spectrum antitumor, antiparasitic and antiprotozoan activity.

References

  • Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Han J.W. et al. Cancer Res. 2000, 60, 6068.
  • Apicidin is a histone deacetylase inhibitor with anti-invasive and anti-angiogenic potentials. Kim S.H. et al. Biochem. Biophys Res Commun. 2004, 315, 964.
  • Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase. Darkin-Rattray S.J. et al. Proc Nat Acad Sci. 1996, 93, 13143.

Other Products

Related products