Anhydroepiophiobolin A

Anhydroepiophiobolin A

$301.00 - 1 mg

$1,055.00 - 5 mg

All prices in Australian dollars

Code
BIA-A1536
Synonyms
Anhydro-6-epiophiobolin A, 3-
CAS #
90411-20-4
Molecular Formula
C25H34O3
Molecular Weight
382.5
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

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Application Notes

Anhydroepiophiobolin A is a dehydrated analogue of ophiobolin epimerised at the C6 position. Anhydroepiophiobolin A is the major terminal degradation product of ophiobolin A and is co-produced with other ophiobolins in many Bipolaris species. Prior to 1984, references to “anhydroophiobolin” almost certainly refer to anhydroepiophiobolin A as the epimerisation at C6 was not well recognised. Under controlled degradation conditions both anhydroepiophiobolin A and anhydroophiobolin A are observed, but the latter is a minor component readily epimerised to anhydroepiophiobolin A. Like all ophiobolins, anhydroepiophiobolin A possesses a broad biological profile with antibacterial, antifungal, antitumor, herbicidal and nematocidal activities.

References

  • Isolation of ophiobolin A and its analogs as inhibitors to photosynthesis. Kim J-M.K. et al., Agric. Biol. Chem. 1984, 48, 803.

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