L-3-Aminoglutarimide ((L)-2-Aminopiperidine-2,6-dione) is the cyclic amine formed by the dehydration of the amino acid, glutamine. Glutarimides represent an important class of antifungal microbial metabolites, including cycloheximide and actiphenol and the core element of the immunodulator, pomaliomide there is little in the literature describing the occurrence and role of this cyclic metabolite. While other cyclic amino acids such as homoserine lactones proved the basis of our understanding of bacterial quorum sensing. The discovery of a biological role of L-3-aminoglutarimide has been unexplored.