$221.00 - 1 mg
$774.00 - 5 mg
All prices in Australian dollars
- (+)-Ambuic acid
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in methanol or DMSO
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Ambuic acid is an antifungal cyclohexanone metabolite produced by Pestalotiopsis sp. Ambuic acid inhibits the biosynthesis of quorum sensing peptides in Gram-positive bacteria. Ambuic acid may exert anti-inflammatory action by blocking the activation of the ERK/JNK MAPK signaling pathway, without the involvement of the p38 MAPK or NF-κB signaling pathways. Ambuic acid demonstrates potent antiproliferative activity.
- Ambuic acid, a highly functionalized cyclohexenone with antifungal activity from Pestalotiopsis spp. and Monochaetia sp. Li J.Y. et al. Phytochem. 2001, 56, 463.
- Ambuic acid inhibits the biosynthesis of cyclic peptide quormones in gram-positive bacteria. Jiro N. et al. Antimicrob. Agents Chemother. 2009, 53, 580.
- Anti-inflammatory action of ambuic acid, a natural product isolated from the solid culture of Pestalotiopsis neglecta, through blocking ERK/JNK mitogen-activated protein kinase signaling pathway. Zhang Q. et al. Exp. Ther. Med. 2018, 16, 153.