Actagardin

Actagardin

$276.00 - 1 mg

$966.00 - 5 mg

All prices in Australian dollars

Synonyms
A 3802-IV-3, Actagardine, Gardimycin, NVB 302
CAS #
59165-34-3
Molecular Formula
C81H124N20O24S4
Molecular Weight
1890.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

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Application Notes

Actagardin is a high molecular weight tetracyclic antibiotic produced by several species of Actinoplanes. Actagardin is an antibiotic in which the macrocyclic rings are formed by thioether, rather than disulphide, bridges. Actagardin is a potent Gram positive and Gram negative antibiotic. Actagardin acts by inhibition of peptidoglycan biosynthesis.

References

  • Gardimycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies. Parenti F. et al., J. Antibiot. 1976, 29, 501.
  • Gardimycin, a new antibiotic from Actinoplanes. II Isolation and preliminary characterisation. Coronelli C. et al., J. Antibiot. 1976, 29, 507.

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