Acetyl-4-hydroxy-L-proline, trans-1-

Acetyl-4-hydroxy-L-proline, trans-1-

$100.00 - 5 mg

$350.00 - 25 mg

All prices in Australian dollars

Code
BIA-A2372
Synonyms
(5R)-1-Acetyl-5-hydroxy-L-proline
CAS #
2235464-65-8
Molecular Formula
C7H11NO4
Molecular Weight
173.17
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Application Notes

trans-N-Acetyl-4-hydroxyproline (oxaceprol) is an atypical inhibitor of inflammation and useful for the treatment of diseases affecting the connective tissues such as osteoarthritis. trans-N-Acetyl-4-hydroxyproline reduces leukocyte adherence in vivo and leukocyte infiltration in mouse AiA, indicating an effect on synovial microcirculation.

References

  • Oxaceprol, an atypical inhibitor of inflammation and joint damage. Ionac M. et al. Pharmacol. Res. 1996, 33, 367.
  • Oxaceprol, an atypical inhibitor of inflammation, reduces leukocyte adherence in mouse antigen-induced arthritis. Veihelmann A. et al. Acta Orthop. Scand. 2001, 72, 293

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