Acetyl-4-hydroxy-L-proline, trans-1-
Acetyl-4-hydroxy-L-proline, trans-1-
$100.00 - 5 mg
$350.00 - 25 mg
All prices in Australian dollars
- Code
- BIA-A2372
- Synonyms
- (5R)-1-Acetyl-5-hydroxy-L-proline
- CAS #
- 2235464-65-8
- Molecular Formula
- C7H11NO4
- Molecular Weight
- 173.17
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in methanol or DMSO
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Application Notes
trans-N-Acetyl-4-hydroxyproline (oxaceprol) is an atypical inhibitor of inflammation and useful for the treatment of diseases affecting the connective tissues such as osteoarthritis. trans-N-Acetyl-4-hydroxyproline reduces leukocyte adherence in vivo and leukocyte infiltration in mouse AiA, indicating an effect on synovial microcirculation.
References
- Oxaceprol, an atypical inhibitor of inflammation and joint damage. Ionac M. et al. Pharmacol. Res. 1996, 33, 367.
- Oxaceprol, an atypical inhibitor of inflammation, reduces leukocyte adherence in mouse antigen-induced arthritis. Veihelmann A. et al. Acta Orthop. Scand. 2001, 72, 293