Acetoxypolygodial
Application Notes
Acetoxypolygodial is a drimane sesquiterpene isolated from the leaves and stems of Tasmannia lanceolata and bark of Canella winterana, and present in other plant species. Acetoxypolygodial is antifungal and weakly cytotoxic, and is potently active against Plasmodium falciparum (IC50 2.53 ug/mL).
References
- Isolation and characterization of 1β-acetoxypolygodial from Tasmannia lanceolata. Deans R.M. et al., Asian J. Org. Chem. 2014, 3, 1193-1196.
- Antiplasmodial and cytotoxic activites of drimane sesquiterpenes from Canella winterana. Grace M.H. et al., Nat. Prod. Commun. 2010, 5, 1869.