$158.00 - 5 mg
$553.00 - 25 mg
All prices in Australian dollars
- 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside, AIC-Riboside, AICA-Riboside, AICAr, Acadra, Arasine, GP 1-110, NSC 105823
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Sluble in water and DMSO
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Acadesine is an adenosine-regulating agent that increases bioavailability of adenosine that has been tested clinically for cardioprotective indications and hematologic malignancies. Acadesine activates AMP-activated protein kinase and inhibits platelet aggregation, induces p53-dependendent apoptosis in B cells and regulates cellular uptake of glucose, beta-oxidation of fatty acids, protein synthesis, and the biogenesis of GLUT4 and mitochondria.
- Acadesine: the prototype adenosine regulating agent for reducing myocardial ischaemic injury. Mullane K. Cardiovascular Res. 1993, 27, 43.
- AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2. Chloe P. et al. Neoplasia 2018, 20, 555.
- Acadesine, an adenosine-regulating agent with the potential for widespread indications. Drew B.G. and Kingwell B.A. Expert Opin Pharmacother. 2008, 9, 2137.