Xanthocillin X dimethyl ether

Xanthocillin X dimethyl ether

Xanthocillin X dimethyl ether

$265.00 - 0.5 mg

$930.00 - 2.5 mg

All prices in Australian dollars

Code
BIA-X3147
Synonyms
XDE, Xanthocillin X dimethyl ether, Xanthocillin X permethyl ether
CAS #
4464-33-9
Molecular Formula
C20H16N2O2
Molecular Weight
316.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

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Product Data Sheet

Application Notes

Xanthocillin X dimethyl ether (XDE) is an isonitrile-containing metabolite isolated from the mycelia of Aspergillus sp. first reported by Chugai Pharmaceutical Co., Japan in 1968. XDE is active against Newcastle disease, vaccinia and herpes simplex viruses, and inhibits the growth of Bacillus subtilis. XDE is a thrombopoietin receptor agonist. XDE was patented as an antitumor agent in 1992.

References

  • Antiviral and antitumor antibiotics. V. Antiviral antibiotics; xanthocillin X mono- and dimethyl ether, and methoxyxanthocillin X dimethyl ether. I. Isolation and characterization. Takatsuki A. et al. J. Antibiot. 1968, 21, 671.
  • New antiviral antibiotics, xanthocillin X mono and dimethylether, and methoxy xanthocillin X dimethylether: Biological aspects of antiviral activity. Takatsuki A. et al. J. Antibiot. 1968, 21, 676.
  • Xanthocillins as thrombopoietin mimetic small molecules. Sakai R. et al. Bioorg. Med. Chem. 2005, 13, 6388.

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