Viriditoxin

Viriditoxin

Viriditoxin

$295.00 - 1 mg

$1,035.00 - 5 mg

All prices in Australian dollars

Code
BIA-V3146
Synonyms
(-)-Viriditoxin, (M)-Viriditoxin, SC 28762
CAS #
1381782-08-6
Molecular Formula
C34H30O14
Molecular Weight
662.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol, DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Viriditoxin is a pigment isolated from a range of fungal species including Aspergillus, Cladosporium, Spicaria and a marine-derived Paecilomyces. Viriditoxin activates ATP hydrolysis and swelling in rat liver mitochondria. Viriditoxin exhibits antibacterial activity against Streptococcus iniae and Streptococcus parauberis, major pathogens of aqua-cultured fish, postulated to be via inhibition of FtsZ polymerization. Viriditoxin has insecticidal and cytotoxic properties, inducing G3/M cell cycle arrest and apoptosis.

References

  • Structure of viriditoxin, a toxic metabolite of Apergillus virid-nutans. Weisleder D. et al. Tetrahedron Lett. 1971, 12, 4705.
  • Viriditoxin induces swelling and ATPase by activation of calcium transport in liver mitochondria. Wong D.T. et al. Biochem. Biophys. Res. Comm. 1976, 71, 332.
  • Antibacterial activities of viriditoxin congeners and synthetic analogues against fish pathogens. Noh T.H. et al. Bioorg. Med. Chem. Lett. 2017, 27, 4970.

Other Products

Related products