Verlamelin A

Verlamelin A

$200.00 - 0.50 mg

$698.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-V2930
CAS #
1619244-34-6
Molecular Formula
C45H71N7O11
Molecular Weight
886.09
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.
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Application Notes

Verlamelin A is a complex lipodepsipeptide antibiotic first isolated from Lecanicillium sp. by Nihira and co-workers at Mahidol University Thailand in 2014. Verlamelin A is active against phytopathogenic fungi, including Aspergillus versicolor and Curvularia australiensis. Verlamelin A is also a potent inhibitor of Colletotrichum asianum (MIC 5-10 μg/mL). Verlamelin A is active against HSV-1 with an IC50 of 16.7 μM.

References

  • Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp.. Ishidoh K. et al. J Antibiot 2014, 67, 459.
  • Antifungal and antiviral cyclic peptides from the deep-sea-derived fungus Simplicillium obclavatum EIODSF 020. Liang X. et al. J Ag Food Chem 2017, 65, 5114.
  • Peptides from the soft coral-associated fungus Simplicillium sp. SCSIO41209. Dai Y. et al. Phytochem 2018, 154, 56.

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