Valinomycin
Application Notes
Valinomycin is a hydrophobic cyclodepsipeptide with potent antitumor activity. Valinomycin is a highly selective potassium ionophore and this action leads to a diverse range of profound cell membrane effects. More recently, valinomycin has found application as a biosensor to detect to detect potassium efflux.
References
- K+-selective nanospheres: maximising response range and minimising response time. Ruedas-Rama M.J. & Hall E.A. Analyst. 2006, 131, 1282.
- Potentiometric combination ion/carbon dioxide sensors for in vitro and in vivo blood measurements. Collison M.E. et al., Anal Chem. 1989, 61, 2365.