Tylosin

Tylosin

$96.00 - 5 mg

$335.00 - 25 mg

All prices in Australian dollars

Code
BIA-T1549
Synonyms
Dehydrorelomycin, Tylosin A
CAS #
1401-69-0
Molecular Formula
C46H77NO17
Molecular Weight
916.1
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Moderater water solubility.
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Application Notes

Tylosin is a 16-membered macrocyclic lactone isolated from Streptomyces fradiae in 1961. Tylosin has broad spectrum antibacterial activity and was developed as a veterinary pharmaceutical for treatment of bacterial infections in a range of domestic animals. Tylosin acts by binding to the 50S ribosomal subunit resulting in the inhibition of protein synthesis in bacteria.

References

  • Tylosin, a new antibiotic. I. Microbiological studies McGuire W. S. et al., Antibiot. Chemother. 1961, 11, 328.
  • Tylosin, a new antibiotic. II. Isolation, properties, and preparation of desmycosin, a microbiologically active degradation product. Hamill R. L.et. al Antibiot. Chemother. 1961, 11, 328.
  • The structure of tylosin Morin R. B. et al., Tet. Lett. 1970, 54, 4737.

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