Turonicin A
Application Notes
Turonicin is an amphoteric linear polyene polyketide related to linearmycins isolated from Streptomyces sp. Turonicin features independent pentaene and tetraenone chromophores. Turonicin A exhibits very potent activity against C. albicans (MIC 0.0031 μg/mL) and S. cerevisiae (MIC 0.0008 μg/mL) and moderate activity against Gram-positive bacteria, with no cytotoxicity against human fibroblasts.
References
- Turonicin A, an antifungal linear polyene polyketide from an Australian Streptomyces sp. Chen R. et al. J. Nat. Prod. 2023, 86, 2054



