Tropolone

Tropolone

$56.00 - 25 mg

$195.00 - 100 mg

All prices in Australian dollars

Code
BIA-T2597
Synonyms
2-Hydroxytropone, NSC 89303, Purpurocatechol, α-Tropolone
CAS #
533-75-5
Molecular Formula
C7H6O2
Molecular Weight
122.12
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
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Application Notes

Tropolone, produced by Pseudomonas sp., is a 7-membered ring bearing hydroxy and carbonyl groups which provides a useful scaffold for chemical modification. Tropolone, the causal agent of seedling blight of rice, is a potent root growth and seed germination inhibitor at concentrations as low as 10 ppm. Tropolone has broad pharmacological profile, including insecticidal, antiviral, antibiotic, adrenergic and catechol-​O-​methyl transferase (COMT) inhibitory activities.

References

  • Tropolone natural products. Guo H. et al. Nat Prod Rep. 2019, 36, 1137.
  • Production of tropolone by a Pseudomonas. Lindberg G.D. ET AL. J Nat Prod. 1980, 43, 592.
  • Phytogrowth-​inhibitory activities of tropolone and hinokitiol. Inamori Y. Chem Pharm Bull. 1991, 39, 2378.

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