$155.00 - 0.10 mg
$543.00 - 0.50 mg
All prices in Australian dollars
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO.
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Tropodithietic acid is a potent antibiotic isolated from a Roseobacter strain by Brinkhoff and colleagues at the University of Gottingen, Germany in 2004. Tropodithietic acid is a strong inhibitor of marine bacteria, promoter of algal health and a potent quorum sensing regulator. Tropodithietic acid is a tropone that exists as an interconverting tautomer with thiotropocin, itself isolated in the 1980s as a metabolite from a strain of Pseudomonas. Tropodithietic acid has potent, broad-spectrum anticancer activity, acting via a mechanism similar to polyether antibiotics.
- Antibiotic production by a Roseobacter clade-affiliated species from the German Wadden Sea and its antagonistic effects on indigenous isolates. Brinkhoff T. et al., App. Env. Microbiol. 2004, 70, 2560.
- Computational studies of the tropone natural products, thiotropocin, tropodithietic acid, and troposulfenin. Significance of thiocarbonyl-enol tautomerism. Greer E.M. et al., J. Org. Chem. 2008, 73, 280.
- Thiotropocin, a new sulfur-containing 7-membered-ring antibiotic produced by a Pseudomonas sp. Kintaka K. et al., J. Antibiot. 1984, 37, 1294.